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SERVICES » Pharmaceutical Development » Biotech Services » Stability Programs and ReleaseTesting
The ABC Difference

 

Pharmaceutical Development

Biotech Services
Method Development & Validation
Stability & Release Testing
Analytical Support
Biomarker Panel Analysis
Peptide Mapping

DMPK and Bioanalytical Solutions (GLP)
Method Development & Validation
In-vitro DMPK Services
In-vivo DMPK Services
Bioanalytical Testing

Radiolabeling and Synthesis Solutions
Radiolabeling with GLP Certification
CGMP Services
Phase 0 Development Support
       Management

CMC and QC Solutions (CGMP)
Method Development & Validation
Extractables/Leachables Studies
Trace Analysis & Structural Chemistry
Stability Programs and Release Testing

Drug Development Consulting

Environmental Assessments

Seamless Project Management
through Strategic Partnerships

Stability Programs & Release Testing for Large Molecule Drugs

Unlike small molecule drugs, large molecule drugs are biologically active and therefore, more easily affected by environmental conditions. To ensure an optimally-controlled, fully compliant CGMP environment for stability sample storage and handling, we use a fully validated Rees monitoring system, validated backup temperature and humidity charts and redundant chamber operating systems. We also have a 100% backup power supply to ensure consistent conditions in the event of a power loss.

ABC conducts stability studies in a secure, DEA-licensed stability suite that provides all ICH conditions, as well as photostability and custom conditions. In addition, we have 35,000 cubic feet of stability storage space--a capacity that is equivalent to 10 tractor trailers.


 

Stability Suite

Our "phase-appropriate" approach to stability study design will help move your development program forward without unwarranted delays or expense.

Analytical Techniques

  • Size-exclusion HPLC (SEC HPLC)
  • Reverse Phase (RP HPLC)
  • Ion Exchange HPLC (IEX HPLC)
  • Peptide Mapping
  • Gel Electrophoresis (SDS-PAGE)
  • Isoelectric Focusing Gel Electrophoresis (IEF-PAGE)
  • Bioassay
  • Capillary Electrophoresis (CE)
  • Capillary Isoelectric Focusing (cIEF)
  • Western Blotting
  • MS Analysis of Proteins (MS/MS, Q-Trap, TOF-MS)
  • Glycan Analysis