ABC Laboratories provides GLP-compliant study design, method development and comprehensive bioanalytical support for IND-enabling toxicology studies. Our regulatory and analytical experts will work with your development team to custom-design protocols and assays for rapid, reliable evaluation of drug compound safety.
We collaborate with a variety AALAC-accredited facilities to provide these services, and routinely provide full project management services to expedite the path to first-in-human studies.
Acute Toxicity
- Primary eye irritation
- Primary dermal irritation
- Corrositex in vitro corrosion test
- Acute dermal (limit & full tests)
- Acute oral (up & down procedure)
Subchronic and Chronic General Toxicology
- 14-, 28- 90-day subchronic
- Immunotoxicology assessment
- Chronic toxicity
- Oncogenicity
- Combined chronic toxicity/oncogenicity
Sensitization
- Local lymph node assay (LLNA)
- Buehler Guinea pig sensitization
- Guinea pig maximization test
- Human patch test
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Reproductive & Developmental Toxicology
- Teratology screen
- Segment I, II, III reporductive/development toxicology
- Multigeneration reproductive toxicology
- Male, femal fertility
- Dominant lethality
Neurotoxicology
- Acute neurotoxicity
- Subchronic neurotoxicity
- Functional observational battery
- Cholinesterase inhibition